Monday, February 6, 2012

Tetralogy of Fallot

Picture Courtesy: American Heart Association
The classic form includes four defects of the heart and its major blood vessels:
  • Ventricular septal defect (hole between the right and left ventricles)
  • Narrowing of the pulmonary outflow tract (the valve and artery that connect the heart with the lungs)
  • Overriding aorta (the artery that carries oxygen-rich blood to the body) that is shifted over the right ventricle and ventricular septal defect, instead of coming out only from the left ventricle
  • Thickened wall of the right ventricle (right ventricular hypertrophy
    Factors that increase the risk for this condition during pregnancy include:
    • Alcoholism in the mother
    • Diabetes
    • Mother who is over 40 years old
    • Poor nutrition during pregnancy
    • Rubella or other viral illnesses during pregnancy


      Surgery is now often carried out in infants one year of age or younger with less than 5% perioperative mortality. The open-heart surgery is designed (1) to relieve the right ventricular outflow tract stenosis by careful resection of muscle and (2) to repair the VSD with a Gore-Tex patch or a homograft. Additional reparative or reconstructive surgery may be done on patients as required by their particular cardiac anatomy. (courtesy Wikipedia)

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